Mayo Clinic documents the following in its 45-year study of essential tremor (Rajput, AH et al., Essential tremor in Rochester, Minnesota: A 45-year study. Journal of Neurology, Neurosurgery, and Psychiatry 1984;47:466-470)
A strong association between essential tremor and Parkinson’s disease was reported by Hornabrook and Nagurney. They noted that the risk of developing Parkinson’s disease was 35 times higher in those patients who had essential tremor as contrasted to those who did not. Barbeau and Pourcher have reported a strong family history of essential tremor in those Parkinsonian patients whose disease began at a relatively young age.
There is a subgroup of individuals where clinical differentiation between benign essential tremor and early-onset Parkinson’s disease is not possible. Even if it were possible to diagnose an ultra-early Parkinson’s disease, there was nothing medicine had to offer until the Parkinson’s disease progressed to the point of needing drug intervention. This treatment was held off as long as possible since the drugs had side effects and did nothing to change the course of Parkinson’s disease.
As noted in a paper published this year,
“Parkinson’s disease is associated with the depletion of serotonin, dopamine, norepinephrine, epinephrine, thiols (homocysteine, L-methionine, S-adenosyl-L-methionine, S-adenosyl-homocysteine, cystathione, L-cysteine, and glutathione), L-tyrosine, and L-tryptophan, and these depletions represent relative nutritional deficiencies (RNDs) where systemic nutritional synthesis requirements cannot be achieved on a normal or optimal diet.” (Hinz, M. et al., The Parkinson’s disease death rate: carbidopa and vitamin B6. Clinical Pharmacology: Advances and Applications 2014:6 161–169, see attached.)
Contrary to the Mayo Clinic assertion, if there is neurological dopamine damage, a “dopamine challenge” will be positive. This is an effective tool for objectively sorting out which person have benign essential tremor and which have ultra-early Parkinson’s disease that does not have the intensity of symptoms required for diagnosis.
All of the ultra-early Parkinson’s disease individuals need to be fully stabilized on the amino acids as soon as possible. Refer to the list of substances (found two paragraphs above) that become depleted during the course of Parkinson’s disease. Depletion of each one of these substances represents a relative nutritional deficiency since their restoration to optimal levels requires administration of nutrients in amounts that are greater than can be attained on an ideal diet.
Proper nutritional management (without drugs since drugs cause long-term deterioration) of the person suffering with Parkinson’s disease prevents the numerous nutritional collapses which most physicians confuse with progression of the disease.
These substances are already deficient in ultra-early stage of Parkinson’s disease. Every day that the nutritional deficiency is allowed to progress without proper management is another day where overall function will move a little further from optimal.
All of the problems associated with Parkinson’s disease are the result of Relative Nutritional Deficiencies (RND). Drugs deplete nutrients so they are not an appropriate management choice. At Brain and Body Wellness Center we manage Relative Nutritional Deficiencies without prescription drugs.
To find out how we can help you, please contact our office at 972-248-0780